Serena is a misanthropic microbiologist. She’s great with bacteria, but her interactions with fellow humans are strained at best. After going too far with a colleague, Serena is forced into intensive sensitivity training, where she is assigned a personal sensitivity coach named Caroline. Caroline is a bubbly behavioral psychologist who makes friends everywhere she goes. At first Serena can’t stand Caroline, but eventually the two form an unlikely friendship and begin to influence each other in unexpected ways.