In the 1950s, America was riding high until a debilitating virus, Polio, began attacking young children in record numbers. Families lived in fear of public places, and the March of Dimes Foundation poured millions of dollars into research for a cure. One man, Jonas Salk, worked day and night for six years sacrificing his personal life to perfect his Polio vaccine, standing up to the traditional medical establishment, the media, and big money interests bent on funding their own medicines. When science is "run like a business" we see surprising results, but we must also reckon the human cost. In the end, only Salk's compassion and dedication keep him going on a quest to save the children of the world.