Rosalind Franklin was one of the four scientists whose work was most responsible when the key to heredity, the molecular structure of DNA, was discovered. She died not long after at the age of 37. When the Nobel Prizes were given out and the book The Double Helix was written by Nobel Laureate James Watson, Rosalind Franklin's work was minimized and her character distorted in the public eye. One woman, Anne Sayre, a friend of Franklin, conducts an investigation to find out the true contribution she made to science and restores not only Franklin's glory as a scientist but her warmth and fascination as a person.